GHK-Cu is one of the most studied copper-binding peptides in laboratory research. This reference page collects its core molecular data and describes, strictly in an in-vitro context, why it is used as a research material. No human or therapeutic use is described or implied.
Identity and molecular data
- Name: GHK-Cu — the glycyl-L-histidyl-L-lysine copper(II) complex
- Peptide sequence: Gly-His-Lys (GHK), a tripeptide
- CAS number (copper complex): 49557-75-7
- Free peptide formula: C₁₄H₂₄N₆O₄ (GHK), molecular weight approximately 340.4 g/mol
- Copper(II) complex: commonly reported molecular weight approximately 403.9 g/mol
The peptide portion is a short sequence of glycine, histidine and lysine; the histidine and terminal amine provide the coordination site that binds copper(II), giving the characteristic blue complex.
Why it is used as a research material
GHK-Cu is used in vitro as a defined copper-delivery tripeptide in connective-tissue, fibroblast and skin-model research, and in studies of copper coordination chemistry. As a research reagent it offers a well-characterised, reproducible way to introduce a copper-peptide complex into a defined experimental system. This page describes areas of laboratory study only and makes no claim about outcomes or efficacy.
Handling and quality
Like other lyophilized peptides, GHK-Cu should be stored cold, dry and away from light, and reconstituted using an appropriate solvent under aseptic technique. Each research batch should be supplied with a certificate of analysis confirming identity and >99% HPLC purity — see our COA guide.
Browse the research-grade GHK-Cu product page or more molecular references in the Peptide Science section.
For research use only. Supplied strictly for in-vitro laboratory and research purposes and not for human or animal consumption. Nothing here describes or implies any therapeutic use.
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